First, a cross-sectional design was applied to investigate the short term mentalhealth influence of COVID-19; however, long term impact, especially post-traumatic stress disorder, might occur with the COVID-19 progression. Second, psychological assessment was only based on online surveys and self-reporting tools, and there may be some deviation. In conclusion, the overall mental health status of the ICU practitioners is worrying. In addition, among the ICU practitioners, the mental health status in the COVID-19 group is better than that of the non-COVID-19 group, and the reasons may vary. Moreover, for the medical workers in the COVID-19 rescue operation, we should select those who have enough related experience and give them adequate health protection training and better working conditions to empower resilience and psychological well-being