The oviduct of mammals has long been recognised as a vital organ for successful reproduction. Animal models from bovine, ovine, porcine, and equine oviducts have shown to be superior for studying gamete physiology, fertilisation, and early embryonic development. Surgical manipulation of the reproductive tract, estrous cycle manipulation, gamete cryopreservation, and AI, as well as in vitro fertilisation and embryo development, are all possible in livestock species. Although most cattle reproductive technology was created to enhance production animal agriculture, these approaches are a gold mine of information for researchers trying to figure out how the oviduct affects gamete activity. The protein, lipid, carbohydrate, enzyme, and electrolyte compositions of oviduct secretions obtained from in vitro tissue cultures or indwelling oviduct catheters have been used for analyses to define the secretions' protein, lipid, carbohydrate, enzyme, and electrolyte compositions during the estrous cycle or in response to hormone treatment.