Nephrotic Syndrome (NS) is a common manifestation of glomerular disease. It is the most common kidney disease in children with an annual incidence of 2-7 per 100,000 children in high income regions. In adult, although less frequent, NS is also a main manifestation of glomerular disease with an annual incidence of 3 per 100,000. In both populations, idiopathic NS is usual, accounting for 80-90% of cases. Minimal Change Disease (MCD) is the leading cause of idiopathic MS in children while Membranous Glomerulopathy (MG) and Focal and Segmental Glomerulosclerosis (FSGS) are more common in adult