A Small Prospective Randomized Double-Blind Placebo Controlled Trial Evaluating the Efficacy of Postoperative Use of Elastomeric Pain Pumps Following Laparoscopic Ventral Hernia Repair

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Ventral Hernia (VH) is a common medical problem in the United States, with about 100,000-150,000 VH repairs performed annually. Over time, VH repair techniques have evolved, with a shift from open sutured repair to open mesh repair to laparoscopic mesh repair in an attempt to lower recurrence rates and improve recovery. Most open and laparoscopic techniques use mesh to bridge the defect and produce a tension-free repair. Based upon the open underlay technique defined by Stoppa and Rives, LeBlanc introduced Laparoscopic Ventral Hernia Repair (LVHR) in 1993. Several large studies have shown improved overall outcomes, including recurrence rates, postoperative complications, length of stay and the time needed to return to daily activities. However, postoperative pain remains a significant issue following LVHR. In recent years, there has been a shift away from the search for the “perfect” analgesics towards combination techniques. In order to decrease the dose of narcotics or non-narcotic analgesics, investigators introduced local anaesthetics in the last few years in a single dose wound infiltration for acute pain management. The combined effect of local anaesthetics and opioids may offer advantages by decreasing the dose of narcotics, which theoretically leads to fewer side effects and better pain control. This technique has gained popularity in recent years because of the aforementioned advantages. Execution of this technique generally utilizes elastomeric pain devices to administer a continuous infusion of local anaesthetic in proximity to or within the surgical site. This method has yielded promising results in other surgical procedures, including open inguinal hernia repair, segmental or total colectomy, thoracotomy, and gynaecology oncologic surgery involving midline laparotomy. For this prospective randomized double-blind placebo-controlled trial, we focused on the specific anatomical location of elastomeric pain pump implantation and the subsequent relief of postoperative pain. The primary objective was to investigate if a continuous, bilateral preperitoneal infusion of a local anaesthetic would reduce both postoperative pain and narcotic pain medication use following LVHR.